LAIR-1 shedding from human fibroblast-like synoviocytes in rheumatoid arthritis following TNF-α stimulation
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چکیده
منابع مشابه
Effects of berberine on human rheumatoid arthritis fibroblast-like synoviocytes.
Activated rheumatoid arthritis fibroblast-like synoviocytes (RAFLSs) play an important role in the initiation and progression of rheumatoid arthritis (RA). Rapid proliferation and defective apoptosis of RAFLSs are two main mechanisms contributing to synovial hyperplasia. Berberine, the major constituent of Coptidis Rhizoma, has been widely used as an antitumor and anti-inflammation agent. Here ...
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INTRODUCTION Chemerin is a chemotactic agonist identified as a ligand for ChemR23 that is expressed on macrophages and dendritic cells (DCs). In this study, we analyzed the expression of chemerin and ChemR23 in the synovium of rheumatoid arthritis (RA) patients and the stimulatory effects of chemerin on fibroblast-like synoviocytes (FLSs) from RA patients. METHODS Chemerin and ChemR23 express...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2018
ISSN: 0009-9104
DOI: 10.1111/cei.13100